Acetaminophen Tramadol MedFacts

Acetaminophen/Tramadol

Acetaminophen/Tramadol is used for:

Short-term treatment (5 days or less) of pain.

Acetaminophen/Tramadol is an analgesic combination. It works in certain areas of the brain and nervous system to decrease pain. The combination may provide better pain relief than either medicine alone.

Do NOT use Acetaminophen/Tramadol if:

• you are allergic to any of the ingredients contained in Acetaminophen/Tramadol or any other codeine or morphine related medicine (eg, codeine, oxycodone, hydrocodone, dihydrocodeine, hydromorphone)
• you have severe diarrhea due to taking an antibiotic
• you are intoxicated with alcohol, other opioids or narcotics (eg, morphine, codeine), sedatives or sleeping medicines (eg, temazepam, zolpidem), or other medicines
• you are taking nefazodone or carbamazepine
• you have liver problems
• you are taking any other medicine containing tramadol or acetaminophen

Contact your health care provider as soon as possible if any of the above applies to you.

Consider before using Acetaminophen/Tramadol

Medical Conditions

There are medical conditions that can influence usage of Acetaminophen/Tramadol . Tell your doctor or pharmacist if any of the medical conditions below applies to you:

• if you are either pregnant or planning to become pregnant
• if you are breast-feeding
• if you are taking any prescription (especially depression medicines) or nonprescription medicine, herbal preparation, or dietary supplement
• if you are allergic to medicines, foods, or other substances
• if you have a history of alcoholism, substance abuse, or if you consume more than 3 alcoholic drinks per day
• if you have considered or attempted suicide
• if you have or recently have had any head injury, brain injury or tumor, increased pressure in the brain, infection of the brain or nervous system, epilepsy, or seizures
• if you have asthma or other lung or breathing problems
• if you have or have a history of stomach or intestinal problems, chronic inflammation or ulceration of the bowel, or if you have had recent abdominal surgery
• if you have heart problems, liver problems (eg, hepatitis), kidney problems, thyroid problems, enlargement of the prostate gland, or urinary problems

Drugs Interaction

There are medicines that may interact with Acetaminophen/Tramadol . Inform your health care provider if you are taking any other medicines, in particular any from the list below:

• Carbamazepine because the effectiveness of Acetaminophen/Tramadol may be decreased and the risk of seizures may be increased
• Certain medicines for mental or mood disorders (eg, olanzapine, haloperidol), cyclobenzaprine, isoniazid, other opioid pain medicine (eg, codeine, hydrocodone), phenothiazines (eg, promethazine), sleeping medicines (eg, zolpidem), tricyclic antidepressants (amitriptyline), or weight loss medicines (eg, phentermine) because side effects, including excessive drowsiness, trouble breathing, liver problems, or seizures may be increased
• Linezolid, monoamine oxidase (MAO) inhibitors (eg, phenelzine), nefazodone, selegiline, or SSRIs (eg, fluoxetine) because they may cause serious and sometimes fatal reactions including restlessness, fever, excessive sweating, confusion, twitching, and seizures
• Oral anticoagulants (eg, warfarin) because side effects, including bleeding, may be increased by Acetaminophen/Tramadol
• Digoxin because the risk of side effects, including nausea, vomiting, or slow heartbeat, may be increased by Acetaminophen/Tramadol

This may not be a complete list of all interactions that may occur. Clarify with your health care provider whether Acetaminophen/Tramadol may interact with other medicines you take. Also, consult your health care provider in advance if you are going to start, stop, or change the dose of any medicine.

Acetaminophen/Tramadol Usage Guidelines

You should use Acetaminophen/Tramadol as recommended by your doctor. Read the medicine's label for precise dosing instructions.

• Take Acetaminophen/Tramadol by mouth with or without food.
• Do not use Acetaminophen/Tramadol for more than 5 days unless advised to do so by your doctor.
• Do not take more than 8 tablets per day. Do not take more than 4 tablets per day if you have kidney problems.
• If you miss a dose of Acetaminophen/Tramadol , take it as soon as you get it remembered. However, if it is almost time for the next dose, ignore the missed one and get back to your normal dosing schedule. Do not take 2 doses at the same time.

Ask your health care provider any questions you may have about how to use this medicine.

Important safety information on tramadol

• Acetaminophen/Tramadol may cause drowsiness and dizziness. There effects may be worsened when this medicine is taken with aclohol or other medicines. Use Acetaminophen/Tramadol with caution. Refrain from driving or performing other possibly dangerous activities until you know how you react to it.
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Acetaminophen/Tramadol ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Acetaminophen/Tramadol may cause dizziness; alcohol, hot weather, exercise, or fever may increase this effect. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of this effect.
• Tell your doctor or dentist that you take Acetaminophen/Tramadol before you receive any medical or dental care, emergency care, or surgery.
• Acetaminophen/Tramadol has acetaminophen in it. Before you start any new medicine, check the label to see if it has acetaminophen in it too. If it does or if you are not sure, check with your doctor or pharmacist.
• Talk to your doctor before you take Acetaminophen/Tramadol if you drink more than 3 drinks with alcohol per day. Acetaminophen/Tramadol may cause stomach bleeding. Your risk may be greater if you drink alcohol while you are using Acetaminophen/Tramadol .
• Use Acetaminophen/Tramadol with caution in OLDER PATIENTS, because they may be more sensitive to its effects.
• Acetaminophen/Tramadol should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: Acetaminophen/Tramadol has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Acetaminophen/Tramadol while you are pregnant. Acetaminophen/Tramadol is found in breast milk. Do not breast-feed while taking this medicine.

When used for long periods of time or at high doses, Acetaminophen/Tramadol may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Acetaminophen/Tramadol stops working well. Do not take more than prescribed.

Some people who use Acetaminophen/Tramadol for a long time without a break may develop a physical need to continue taking it. This is known as physical DEPENDENCE. If you suddenly stop taking Acetaminophen/Tramadol , you may experience WITHDRAWAL symptoms including anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea and vomiting; pain; rigid muscles; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping.

Side effects may be caused by Acetaminophen/Tramadol

All medicines may cause side effects, but many people have no, or minor, side effects. Consult your doctor if any of the most COMMON side effects from the list below persist or start bothering you:

Constipation; diarrhea; dizziness; drowsiness; increased sweating; loss of appetite; nausea.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe seizures (convulsions).

It sholud be noted, that this is not a full list of possible side effects. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include bluish skin; cold clammy skin; difficult or slow breathing; drowsiness leading to unresponsiveness or coma; excessive sweating; loss of function in the heart and lungs; nausea and vomiting; pinpoint pupils; seizure (convulsions); stomach or intestinal pain.

Acetaminophen/Tramadol storage instructions:

Store Acetaminophen/Tramadol at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acetaminophen/Tramadol out of the reach of children and away from pets.

General information:

• If you have any questions on Acetaminophen/Tramadol , please consult your doctor, pharmacist, or health care provider.
• Acetaminophen/Tramadol is supposed to be used only by the patient it is prescribed to. Do not share it with other people.
• If your symptoms do not improve or even become worse, inform your doctor.

This information is a summary only. It does not contain all information about Acetaminophen/Tramadol . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.